Once rivals in school, two brilliant doctors reunite by chance — each facing life's worst slump and unexpectedly finding solace in each other.

Within the palace exist troublemaking princes who cause nothing but headaches for the royal family and are about to be turned into proper crown princes. Their mother, Im Hwa Ryeong, is the wife of a great king. But instead of having an aura of elegance and grace, she is a prickly, sensitive, and hot-tempered queen. Once more serene, she changed since people kept pushing her buttons. She is a queen who sometimes abandons her pride and is even known to swear! Every day of her life is full of trials, but she withstands them, all for the sake of her children.

Story follows a group of physical therapists, nurses, radiological technologists and trainees. Ye Jae-Wook works as a physical therapist and also teaches in the same field. He begins to work as a team leader at a hospital. Woo Bo-Young has been working as a physical therapist for 3 years. She wanted to become a poet, but due to her poor family background she studied to become a physical therapist. Shin Min-Ho is a trainee, but he isn't interested in physical therapy. His grades weren't good enough for medical school and his parents, who are both doctors, made him study physical therapy.