After a global pandemic destroys civilization, a hardened survivor takes charge of a 14-year-old girl who may be humanity's last hope.

A group of heroic firefighters at Seattle Fire Station 19—from captain to newest recruit—risk their lives and hearts both in the line of duty and off the clock. These brave men and women are like family, literally and figuratively, and together they put their own lives in jeopardy as first responders to save the lives of others.

A reckless flight attendant with an alcoholism problem wakes up in the wrong hotel, in the wrong bed, with a dead man - and no idea what happened. Unable to piece the night together, she begins to wonder if she could be the killer.